Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/420370
Title: | Design synthesis and evaluation of peptide conjugates for alzheimer 8217 s amyloid disruption |
Researcher: | Mondal, Tanmay |
Guide(s): | Mandal, Bhubaneswar |
Keywords: | Chemistry Chemistry Applied Physical Sciences |
University: | Indian Institute of Technology Guwahati |
Completed Date: | 2019 |
Abstract: | The cleavage of the backbone of a peptide or protein related disease may treat the disease to heal We noted that supramolecular interactions govern all of the protein aggregation Therefore we hypothesized that a novel way of intervention may be outlined by combining the supramolecular interactions and chemical reactions So we engineered a small peptide to cleave the disease prone Amyloid b Ab selectively and its toxic oligomers at the enzymatic cleavage sites especially that of a secretas... |
Pagination: | Not Available |
URI: | http://hdl.handle.net/10603/420370 |
Appears in Departments: | DEPARTMENT OF CHEMISTRY |
Files in This Item:
File | Description | Size | Format | |
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01_fulltext.pdf | Attached File | 40.15 MB | Adobe PDF | View/Open |
04_abstract.pdf | 86.54 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 309.71 kB | Adobe PDF | View/Open |
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