Implications of self assembly and metal binding on the bactericidal potential of synthetic amphiphiles

Abstract

The unabated menace of antibiotic resistant pathogenic bacteria has fueled the need to develop potent antibacterials that can contravene the resistance barrier To address this contemporary healthcare issue the present work highlights the prospect of synthetic amphiphiles whose unique design enabled integration of multiple attributes in a single molecule so as to provide a distinct edge in annihilation of the target pathogen A salicaldehyde based amphiphile C1 exhibiting broad spectrum bac...