Multifaceted approach for cancer therapeutics

Abstract

Cellular genetic and epigenetic modifications leading to uncontrolled proliferation results in tumor mass formation At tumor hypoxic core cells barely proliferate resulting in drug resistance Effective monotherapies as well as combination therapies are being employed for remission of such tumors However chemotherapeutic approaches have limitations mainly due to poor solubility of anticancer drugs lack of selectivity and multi drug resistance Alternative therapeutic strategies including...