Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/419137
| Title: | Bacillus subtilis: a microbial cell factory for human interferon gamma production and process development |
| Researcher: | Kumar, Nitin |
| Guide(s): | Dasu, Veeranki Venkata |
| Keywords: | Engineering Engineering and Technology Engineering Biomedical |
| University: | Indian Institute of Technology Guwahati |
| Completed Date: | 2019 |
| Abstract: | The B. subtilis WB800N microbial cell factory was tackled at three levels for enhanced extracellular human interferon gamma production namely: 1) genetic level 2) substrate, medium components and extracellular cultivation environment level and 3) process operation level. The genetic level modulation of the B. subtilis WB800N physiology was performed by designing three human interferon gamma genes (IFNγ) with different optimum codon usage, RNA free energy and secondary structures. At substrate |
| Pagination: | Not Available |
| URI: | http://hdl.handle.net/10603/419137 |
| Appears in Departments: | DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_fulltext.pdf | Attached File | 21.62 MB | Adobe PDF | View/Open |
| 04_abstract.pdf | 91.87 kB | Adobe PDF | View/Open | |
| 80_recommendation.pdf | 168.25 kB | Adobe PDF | View/Open |
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