Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/417059
Title: Stereoselective Total Synthesis of Resorcyclic Acid Lactones Tumonoates and Synthesis of Tamoxifen Analogue Functionalized Pyrroles and Piperazine Derivatives
Researcher: Nagalatha, G
Guide(s): Venkat Narsaiah,A
Keywords: Chemistry
Chemistry Applied
Physical Sciences
University: Osmania University
Completed Date: 2022
Abstract: newlineAbstract newlineThe Thesis entitled quotStereoselective Total Synthesis of Resorcylic acid lactones, Tumonoates and Synthesis of Tamoxifen analogue, Functionalized Pyrroles and Piperazine derivatives newlinequot newline consists of four chapters. First chapter contains Introduction to Secondary metabolites-and#946;-Resorcylic acid Lactones and Tumonoates and their importance, second chapter deals with the synthesis of Chochliomycin B, third chapter has two parts in which part-A describes the synthesis of Tumonoic acid A and its derivatives, whereas part-B deals with the synthesis of Tamoxifen analogue and the fourth chapter also contains two parts in which part-A deals with the synthesis of functionalized Pyrroles, whereas part-B deals with the synthesis of Piperazine derivatives. newline CHAPTER-I newlineIntroduction to secondary metabolites- and#946; -Resorcylic acid Lactones and Tumonoates: newlineThe natural products are the chemical compounds which are found in nature and produced by terrestrial plants and microorganisms or marine organisms like bacteria and fungi. These compounds usually have a pharmacological or biological activity and useful in drug development strategy. These natural products include polyketides, terpinoids, alkaloids and antibiotics etc. newlineResorcylic acid lactones (RALs) as a natural product class: (Fungal metabolites): newlineResorcylic acid lactones are benzomacrolides, isolated from the metabolites of various fungal newlinestrains, represented by and#946;-resorcylic acid unit fused by a 14 membered macrolactone. newline newline newline
Pagination: 335p
URI: http://hdl.handle.net/10603/417059
Appears in Departments:Department of Chemistry

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01_title.pdfAttached File131 kBAdobe PDFView/Open
02_prelim pages.pdf903.6 kBAdobe PDFView/Open
03_abstract.pdf1.56 MBAdobe PDFView/Open
04_content.pdf18.97 MBAdobe PDFView/Open
05_chapter1.pdf1.99 MBAdobe PDFView/Open
06_chapter2.pdf15.49 MBAdobe PDFView/Open
07_chapter3.pdf8.21 MBAdobe PDFView/Open
08_chapter4.pdf6.38 MBAdobe PDFView/Open
09_annexures.pdf742.05 kBAdobe PDFView/Open
80_recommendation.pdf6.38 MBAdobe PDFView/Open
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