Development of electrochemical and fluorescence sensors for food additives and clinically significant molecules

Abstract

During the past years, there has been extraordinary acceleration of newlineprogress in the development of sensors which plays a pivotal role in the newlinetechnology driven society. Sensors have found potential applications in newlinediverse fields such as clinical analysis, food quality control, newlineenvironmental monitoring, security, defense etc. Chemical sensors are newlineminiaturized analytical devices that can deliver real-time information newlineabout the presence of specific compounds or ions in complex samples. newlineThey are composed of an active sensing material with a signal transducer. newlineThe analyte recognition process takes place followed by the conversion of newlinechemical information into analytically useful signal. Based on their output newlinesignals, sensors have been classified into different types. newlineElectrochemical and fluorescent sensors due to their high selectivity, newlinesensitivity, simplicity and fast response, have been of great interest. During newlinethe course of the research, five voltammetric sensors and two fluorescence newlinesensors have been developed for various food additives and clinically newlinesignificant compounds. Exploiting the excellent electrochemical properties of newlinemultiwalled carbon nanotubes and conducting polymers, voltammetric newlinesensors have been developed for the analytes, butylated hydroxylanisole, newlineazorubine, ponceau 6R, amaranth and melatonin. Nanosized fluorophores newlineincluding cadmium sulfide quantum dots (CdS QDs) and gold nanoclusters newline(AuNCs) were used for developing fluorescent sensors for sunset yellow and newlinenimesulide. newlineThe thesis entitled Development of electrochemical and newlinefluorescence sensors for food additives and clinically significant newlinemolecules is divided in to ten chapters. newline