Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/409078
Title: | Synthesis of Functionalized 2 H Chromene and Its Biological Studies |
Researcher: | Chakroborty, Subhendu |
Guide(s): | Nayak, Sabita |
Keywords: | Chemistry Chemistry Organic Physical Sciences structural |
University: | Ravenshaw University |
Completed Date: | 2016 |
Abstract: | Heterocycles undoubtedly constitute a dominant class of organic compounds with the widest newlinevariety of classifications.1 They are a very important class of compounds not only being common newlinein biologically active important classes of natural products, for example, alkaloids, vitamins, newlinehormones, and antibiotics but also because of their diverse applications in different fields. Most newlinecommon heterocycles are oxygen, nitrogen and sulfur-containing compounds. Oxygencontaining heterocycles are ubiquitous in nature and can be classified by the number of ring newlineatoms. Chromenes are referred as privileged structures .2 This privileged status is given to newlinethem because of their ability to bind to multiple, unrelated classes of protein receptors as high newlineaffinity ligands by orienting varied substituent patterns in a well-defined three-dimensional newlinespace. Privileged3 newlinestructures exhibit good drug like properties and that led to the formation of newlinenatural product-like combinatorial library4 newlinebased on 2,2-dimethylbenzopyran moieties as the newlinetemplate. The diverse array of biological activities of 2H-chromene containing compounds and newlinethe structural importance of benzopyran moiety has inspired the organic chemistry world for the newlinedevelopment of new and improved synthesis of this molecular scaffold.5 newline newline |
Pagination: | All Pages |
URI: | http://hdl.handle.net/10603/409078 |
Appears in Departments: | Department of Chemistry |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 26.46 kB | Adobe PDF | View/Open |
02_declaration.pdf | 109.73 kB | Adobe PDF | View/Open | |
03_certificate.pdf | 118.02 kB | Adobe PDF | View/Open | |
04_acknowledgement.pdf | 417.03 kB | Adobe PDF | View/Open | |
05_contents.pdf | 73.4 kB | Adobe PDF | View/Open | |
06_list of graph and table.pdf | 359.09 kB | Adobe PDF | View/Open | |
07_chapter 01.pdf | 2.37 MB | Adobe PDF | View/Open | |
08_chapter 02.pdf | 1.97 MB | Adobe PDF | View/Open | |
12_annexure.pdf | 2.65 MB | Adobe PDF | View/Open | |
80_recommendation.pdf | 125.93 kB | Adobe PDF | View/Open | |
i. abstract.pdf | 446.01 kB | Adobe PDF | View/Open | |
iii. coverage of thesis.pdf | 60.35 kB | Adobe PDF | View/Open | |
ii. key words.pdf | 6.43 kB | Adobe PDF | View/Open |
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