Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/398102
Title: | Design and Synthesis of Thienopyrimidine Quinazoline Piperidinedione Analogs to Study their Biological Activity |
Researcher: | Kaliraj, S |
Guide(s): | Jeyalakshmi, R |
Keywords: | Chemistry Chemistry Multidisciplinary Physical Sciences |
University: | SRM Institute of Science and Technology |
Completed Date: | 2022 |
Abstract: | Heterocycles are considered the largest section of chemistry and most of the natural compounds produced has one or other heterocyclic rings as a constitutional part. Recently, researchers are focused on the production of such groups which imitate natural products with specific bioactivity. Further, there is a continuous search in heterocycles for different applications like pharmaceuticals, pesticides, cosmetics, antioxidants, dyestuffs, etc that are progressing well. The development in these compounds also continues to strengthen their role in biological systems and also futuristic functional materials. In heterocyclic chemistry, the compounds containing nitrogen as a heteroatom are regarded as a fascinating class since they show significant developments in physicochemical properties, accepting modifications and diverse activity from the different synthetic approaches. The structural modifications in the compounds at different sites and positions, lead to the bioactivity of pharmacological importance and scope for structure-activity relation. In view of the above, the present investigations focused on the design, synthesis of a few heterocycles containing thienopyrimidine, quinazoline, and piperidindione in a fused form and to investigate their biological activity. These compounds constitute the pharmacophore and few derivatives are known for their therapeutic applications newline |
Pagination: | |
URI: | http://hdl.handle.net/10603/398102 |
Appears in Departments: | Department of Chemistry |
Files in This Item:
File | Description | Size | Format | |
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01_title.pdf | Attached File | 186.89 kB | Adobe PDF | View/Open |
02_declaration.pdf | 187.57 kB | Adobe PDF | View/Open | |
03_certificate.pdf | 194.39 kB | Adobe PDF | View/Open | |
04_acknowledgement.pdf | 190.44 kB | Adobe PDF | View/Open | |
05_content.pdf | 376.58 kB | Adobe PDF | View/Open | |
06_list of graph and table.pdf | 342.41 kB | Adobe PDF | View/Open | |
07_abstract.pdf | 190.29 kB | Adobe PDF | View/Open | |
08_chapter 1.pdf | 583.93 kB | Adobe PDF | View/Open | |
09_chapter 2.pdf | 370.23 kB | Adobe PDF | View/Open | |
10_chapter 3.pdf | 489.43 kB | Adobe PDF | View/Open | |
11_chapter 4.pdf | 727.48 kB | Adobe PDF | View/Open | |
12_chapter 5.pdf | 587.92 kB | Adobe PDF | View/Open | |
13_chapter 6.pdf | 547.94 kB | Adobe PDF | View/Open | |
14_chapter 7.pdf | 503.04 kB | Adobe PDF | View/Open | |
15_chapter 8.pdf | 215.58 kB | Adobe PDF | View/Open | |
16_references.pdf | 7.31 MB | Adobe PDF | View/Open | |
17_list of publications.pdf | 182.9 kB | Adobe PDF | View/Open | |
18_vitae.pdf | 182.1 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 267.61 kB | Adobe PDF | View/Open |
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