Evaluation of Selected Traditional Medicinal Flowers from Marathwada Region against Inflammation

Abstract

The present study was aimed to evaluate selected traditional medicinal flowers from the Marathwada region against inflammation were conducted by Cotton pellet-induced granuloma and Carrageenan-induced paw edema in albino mice.This is the first study from the Marathwada region examining the flower, rather than the leaves, bark, fruit or seeds of Azadirachta indica A. Juss, Calotropis gigantea (L.) W.T. Aiton, Catharanthus roseus (L.) G. Don, Moringa oleifera Lam, Polianthes tuberosa L. and Tamarindus indica L. using water, methanol, chloroform and hexane solvents. newlineOur results showed that maximum percent yield was obtained when Calotropis gigantea was extracted by soxhlet extraction technique with methanol (9.53%) in both methods followed by water (8.08%), chloroform (5.61%) and hexane (1.56%), indicating that the extraction efficiency favors the highly polar solvents. While the Soxhlet technique, with methanol gave (8.13%), followed by water (7.36 %), chloroform (5.61%) and finally hexane (1.56%). newlineOur results showed significantly higher phenolic content in the methanol extract of all tested flower. The phenolic content of Azadirachta indica, Calotropis gigantea, Catharanthus roseus, Moringa oleifera, Polianthes tuberosa and Tamarindus indica flowers in methanol extract was 198.56±0.75, 201.34±0.45, 191.27±0.87, 165.39±0.88, 164.20±0.64, 198.62±0.33 mg GAE/g, respectively, followed by water, chloroform and hexane extracts. The total flavonoid of all tested solvent extracts in the methanol extract of all tested flower was highest at 113.15±0.35, 151.24±0.24, 125.52±0.16, 112.09±0.88, 112.18±0.76, 160.75±0.94 mg QE/g, respectively, followed by water, chloroform and hexane extracts.Among the solvents tested methanol and water were the best solvents for extracting bioactive compounds from all plants flower tested since it resulted in the highest extraction yield and the highest content of flavonoids, phenolics, saponins and alkaloids. In all solvents, methanol showed better results followed by water, chloroform and hex