Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/37532
Title: | Physicochemical Study of Antioxidant Surfactant Interaction: utilization in clotrimazole topical formulation |
Researcher: | Bhardwaj, Varun |
Guide(s): | Sharma, Poonam |
Keywords: | Antioxidants Clotrimazole Formulation Micellization Physicochemical Interaction Surfactants |
Upload Date: | 18-Mar-2015 |
University: | Jaypee University of Information Technology, Solan |
Completed Date: | 23/12/2014 |
Abstract: | Micellar systems hold excellent drug delivery applications due to their capability to solubilize a large number of hydrophobic and hydrophilic molecules In this present work, the mixed micelle formation between three surfactants SDS, CTAB and Triton X 100 and two synthetic lipophilic antioxidants BHA and BHT have been studied in different alcohols and hydroalcoholic mediums ie 100percent 70 percent and 30 percent of MeOH, EtOH and 1 PrOH Early micellization was found with critical micelle concentration CMC shifting towards lower concentration In this context, conductance study, CMC, standard thermodynamic parameters of micellization namely , and have been evaluated at different temperatures Molar volume and compressibility measurements have also been carried out to evaluate the apparent molar volume and#61542;v and apparent molar adiabatic compression and#61542;k of BHA BHT surfactant complex and discussed in terms of the solute solute and solute solvent interactions newline |
Pagination: | |
URI: | http://hdl.handle.net/10603/37532 |
Appears in Departments: | Department of Pharmacy |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 80.02 kB | Adobe PDF | View/Open |
04_acknowledgement.pdf | 357.55 kB | Adobe PDF | View/Open | |
05_list of figures & tables.pdf | 992.96 kB | Adobe PDF | View/Open | |
06_contents.pdf | 216.68 kB | Adobe PDF | View/Open | |
07_chapter 1.pdf | 4.16 MB | Adobe PDF | View/Open | |
08_chapter 2.pdf | 3.22 MB | Adobe PDF | View/Open | |
09_chapter 3.pdf | 3.13 MB | Adobe PDF | View/Open | |
10_chapter 4.pdf | 8.74 MB | Adobe PDF | View/Open | |
11_chapter 5.pdf | 4.09 MB | Adobe PDF | View/Open | |
12_chapter 6.pdf | 404.48 kB | Adobe PDF | View/Open | |
13_publications.pdf | 367.74 kB | Adobe PDF | View/Open | |
14_appendices.pdf | 4.77 MB | Adobe PDF | View/Open | |
2_certificate.pdf | 141.51 kB | Adobe PDF | View/Open | |
3_declaration.pdf | 84.95 kB | Adobe PDF | View/Open |
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