Design Optimization and Evaluation of Polyherbal Formulation Against Microsporum Gypseum

Abstract

The aim of the research done was to Design, optimization and evaluation of polyherbal formulation against Microsporum gypseum, initially evaluation of the antifungal activity of different extracts of Zingiber officinale Rosc. Commonly known as ginger and Sonth, Origanum vulgare L, Cinnamomum aromaticum Nees syn. Cinnamomum cassia Blume commonly known as Chinese cassia, dalchini, Cinchona calisaya Wedd. Jesuit s bark (Engl.) commonly has known as Peruvian bark, Syzygium aromaticum (L) Merr. and M. Perry commonly has known as Laung and lavanga, Trigonella foenum-graecum L. Fenugreek commonly known as methi, Azadirachta indica A. Juss. Commonly known as Neem, Margosa and Nim, Rosemarinus officinalis L. plant species used in Indian traditional medicine was checked against the Microsporum gypseum. The bases behind the selection of plants were their reported ethno botanical uses and traditional utilization in treatment of various skin fungal infections. Successive extraction was carried out with different extracts; extracts were prepared by macerating different powder samples (500 gm) successively at room temperature for 24 hours with petroleum ether (PE), ethyl acetate (EA)... newline