Design Synthesis and Application of Amino acid based Ionic Liquids in Organic Synthesis

Abstract

Ionic liquids (ILs) have been established to be potential environmentally benign alternative versatile tool in the field of green chemistry and have found extensive applications in the organic transformations. Due to many fascinating properties ILs (ability to replace volatile organic solvents or molecular solvents, negligible volatility, enhanced miscibility towards reacting species, increased efficiency of the catalyst, reduced reaction times and, catalyst recyclability) have recognized themselves to be a true alternative of traditional solvents and catalyst. Moreover, the unique properties of ionic liquids can also be altered or designed according to the need. The enormous enthusiasm for ILs as catalysis is not only motivated by the newlinecuriosity of chemists, but also due to the growing awareness of developing greener reactions in catalytic science. There are many advantages to use ILs as alternative solvents in various catalytic processes over newlinetraditional volatile organic solvents. Further, ILs additional advantage of providing an ionic environment to the reactive catalytic species which is not possible with molecular solvents. All this properties led to the recognition of ionic liquids for its ability to dissolve many inorganic and organic materials, their high polarities, thermal stability and immiscibility with many organic solvents. The Chapter-1 thesis describes the synthesis of some novel ionic liquids (ILs)/dipeptide newlinebased ionic liquids as catalysts or reaction media inorganic transformations. Thermal properties studies of synthesized dipeptide based ionic liquids are also discussed. The thesis has been divided into five chapters. The first chapter presents a brief literature survey on the application of common ionic liquids and amino acids based ionic liquids reaction in organic synthesis. Chapter 2 describes the synthesis of a series of novel L-Proline functionalized dipeptide imidazolium ionic liquid by conventional ionic liquid method and characterization by 1H NMR, 13C NMR, and IR spectroscopy.