Studies on synthesis and physicochemical characterization of novel schiff base compounds using berry fruit extracts for cosmeceutical application

Abstract

Chapter 1: This chapter deals with the introduction and literature study of various berry fruits, their compositional structures, their physiological activities along with their cosmeceutical applications. Most of the berry fruits possess the physiological activities such as antioxidant, anti-inflammatory, anti-aging etc. They are loaded with naturally active conmpounds such as flavonoids, tannins, polyphenols etc which are of very high physiological importance. Berry fruits were screened according to their demonstrated antioxidant activity and the fruits with possessing IC50 values were chosen for further studies. Chapter 2: This chapter deals with the studies of berry fruit juices converted into freeze dried powders and for evaluating their physico chemical properties qualitatively and quantitatively. Standardization, identification and evaluation of fruit juice freeze dry powders was performed by studying their pharmacognostical properties and physiological and cosmetic applications. Chapter 3: This chapter deals with the synthesis of Schiff s bases from berry fruit based natural acids. This ecofriendly method was employed with ease to produce compounds which are high in quality, quantity and with efficient antimicrobial and antioxidant activities. The developed, novel, eco-friendly green procedure for the synthesis of Schiff s bases was proved to be efficient and reliable. The spectroscopic characterization had confirmed that the products are comparable in chemical composition with the synthetically produced counterparts. Schiff s bases and completely new compounds were synthesized from 0.01M Sulphuric acid, 0.1% gallic acid and 1.0 % different berry fruit juice freeze dry extracts as catalysts and were characterized by techniques such as FTIR, GC-FID, GCMS and NMR and the structural identifications were confirmed. The resultant compounds produced by the green chemical synthetic methods were confirmed to be equivalent to the compounds produced from the traditional chemical methods.