Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/359223
Title: | Proteome Analysis Of Parkinsonian Mice Treated With Tinospora Cordifolia |
Researcher: | Birla, Hareram |
Guide(s): | Singh, Surya Pratap |
Keywords: | Biochemistry and Molecular Biology Biology and Biochemistry Life Sciences Mice Parkinsonia |
University: | Banaras Hindu University |
Completed Date: | 2021 |
Abstract: | Parkinson s disease (PD), a neurodegenerative central nervous system disorder, is newlinecharacterized by progressive loss of nigrostriatal neurons in basal ganglia. Stress-induced newlinedopaminergic (DAergic) neuronal death in the midbrain region is the primary cause of newlineParkinson s disease (PD). Approximately 2% of the global population aged above 65 years newlineis affected with PD. Various factors are responsible for the death of DAergic neurons, newlineamong which mitochondrial dysfunction, oxidative stress, misfolded protein aggregation, newlineand neuroinflammation are the primary factors. Previous studies regarding PD have newlinesuggested the role of oxidative stress along with neuroinflammation in neurodegeneration. newlineAfter the discovery of L-dopa, multiple drugs were discovered to improve the lifestyle of newlinePD patients, but they failed due to their multiple side effects. newline |
Pagination: | |
URI: | http://hdl.handle.net/10603/359223 |
Appears in Departments: | Department of Biochemistry |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 662.42 kB | Adobe PDF | View/Open |
02_certificate.pdf | 150.17 kB | Adobe PDF | View/Open | |
03_content.pdf | 72.63 kB | Adobe PDF | View/Open | |
04_abstract.pdf | 947.79 kB | Adobe PDF | View/Open | |
05_acknowledgement.pdf | 88.69 kB | Adobe PDF | View/Open | |
06_list of figures and tables.pdf | 89.1 kB | Adobe PDF | View/Open | |
07_abbreviation.pdf | 103.41 kB | Adobe PDF | View/Open | |
08_preface.pdf | 177.17 kB | Adobe PDF | View/Open | |
09_chapter 1.pdf | 1.01 MB | Adobe PDF | View/Open | |
10_chapter 2.pdf | 909.45 kB | Adobe PDF | View/Open | |
11_chapter 3.pdf | 1.03 MB | Adobe PDF | View/Open | |
12_conclusion.pdf | 256.57 kB | Adobe PDF | View/Open | |
13_bibliography.pdf | 345.54 kB | Adobe PDF | View/Open | |
14_appendices.pdf | 9.25 MB | Adobe PDF | View/Open | |
80_recommendation.pdf | 919.21 kB | Adobe PDF | View/Open |
Items in Shodhganga are licensed under Creative Commons Licence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).
Altmetric Badge: