Morphometrical Histopathological and Cytogenetical Ameliorating Effect of Ionidium Suffruticosum Extract on Nicotine Toxicity of Testis in Wistar Albino Rats

Abstract

Affront to any biological system by noxious agents, drugs or xenobiotics causes multifold effects which are manifested in different ways in tissues and organs. Numerous chemicals are known to produce infertility in the male. Their initial targets, however, may be quite different and the ultimate result of the exposure, infertility, may be the result of entirely different toxicological processes. Nicotine, one of the most important acute acting pharmacological agent of tobacco, is one such drug which has potent effect not only on the brain, but also on other target tissues and systems newline