Molecular and genetic studies in cervical Cancer the mechanisms of apoptosis And autophagy pathways

Abstract

The Ph.D. thesis entitled Molecular and genetic studies in cervical cancer: the mechanisms of apoptosis and autophagy pathways includes identification of molecular targets of two investigational drugs. Investigation on two pathways of programmed cell death, apoptosis (type I) and autophagy (type II), are the focus of the thesis. Deregulation of the cellular pathways leading to programmed cell death in mammals can cause a number of diseases, including neurodegenerative diseases, autoimmunity, and most prominently, various cancers. newline