The Study of Pharmacognostical Phytochemical and Biological Activities of Rubus Racemosus Family Rosaceae Roxb

Abstract

The plant Rubus racemosus belongs to the family Rosaceae was selected. A detailed pharmacognostical, toxicological and pharmacological was studied on the plant. The aerial parts of the plant Rubus racemosus were anatomically studied and reported first time. A detailed anatomical description of the anatomical structures were studied. The midrib contains 2-3 layers of epidermis, vascular bundle. Lamina contains mesophyll tissue consists of palisade cells and spongy parenchyma. The vascular bundles are surrounded by dilated hyaline bundle sheath cells. The type of trichomes present is glandular and non-glandular trichomes. All the bundles in petiole are collateral with thick band of sclerenchyma cells abutting the phloem tissues. Stem contains wedge shaped vascular bundles. Sclerenchyma cells are thin walled and wide lumened. The pith is parenchymatous. The powder microscopy of the plant shows unicellular, non-glandular, trichomes, anisocytic type of stomata, parenchyma cells and prismatic type of calcium oxalate crystals. Length and Width of trichomes, leaf constants, physio chemical constants, loss on drying and extractive values were determined. From the observations of the studies performed it could be predicted that the MERR at both 200 mg/kg and 400 mg/kg exhibited significant antiepileptic activity. Petroleum ether, Ethyl acetate, Chloroform, Methanol and Aqueous extracts of Rubus racemosus have showed significant and moderate activity against anti-bacterial and anti-fungal organisms. Based on the results obtained and observation we can infer that the plant under study, Rubus racemosus could be used for the supportive treatment of diabetes mellitus, as the plant also offers effective protection against the attack of free radicals that forms the basis for the development of diabetic complications. And it also showed significant anti-epileptic, anti-bacterial and anti-fungal activity. newline