Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/337443
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dc.coverage.spatial
dc.date.accessioned2021-08-24T04:42:53Z-
dc.date.available2021-08-24T04:42:53Z-
dc.identifier.urihttp://hdl.handle.net/10603/337443-
dc.description.abstractBackground newlineMelanoma is one of the most aggressive type of skin cancer, with high incidence rate and newlinemortality, throughout the world. Despite of noteworthy development in melanoma newlinetreatment, the destructive nature of the disease makes it difficult for clinicians to manage the condition. Hence, there is need remains to achieve improved therapeutic activity and overall survival time using herbal constituents, which can offer improved efficacy over existing chemotherapy, in melanoma therapy. Resveratrol (RV) and piperine (PI) are the model newlinedrugs of choice for their potential antimelanoma activity. However, their clinical application newlineis limited due to their poor pharmacokinetic properties. newline newlineObjectives newlineThe current research work aims to investigate the effect of Cubosomal nanoformulation of newlineRV and PI against Melanoma.Hence the objectives of thestudy are: newline newline1. To formulate, evaluate and optimize RV and PI loaded cubosomal nanoformulation. newline2. To study anticancer activity of optimized cubosomal nanoformulation against newlineMelanoma. newline
dc.format.extent
dc.languageEnglish
dc.relation
dc.rightsuniversity
dc.titleCubosome based nanoformulation of resveratrol and piperine for targeting melanoma
dc.title.alternative
dc.creator.researcherBhaskar Kallappa Kurangi
dc.subject.keywordClinical Pre Clinical and Health
dc.subject.keywordPharmacology and Pharmacy
dc.subject.keywordPharmacology and Toxicology
dc.description.noteesveratrol; Piperine; cubosome; melanoma; cell uptake; pharmacodynamic
dc.contributor.guideSunil Satyappa Jalalpure
dc.publisher.placeBelgaum
dc.publisher.universityKLE University
dc.publisher.institutionFaculty of Pharmacy
dc.date.registered
dc.date.completed2020
dc.date.awarded
dc.format.dimensions
dc.format.accompanyingmaterialNone
dc.source.universityUniversity
dc.type.degreePh.D.
Appears in Departments:Faculty of Pharmacy

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