Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/337441
| Title: | Solubility enhancement system design for transbuccal delivery In vitro characterization and Invivo evaluation of lovastatin |
| Researcher: | Bhuvaneshwari R. Sharannavar |
| Guide(s): | Sunil Satyappa Jalalpure |
| Keywords: | Clinical Pre Clinical and Health Pharmacology and Pharmacy Pharmacology and Toxicology |
| University: | KLE University |
| Completed Date: | 2020 |
| Abstract: | Background: Lovastatin (LVS); HMG CoA inhibitor, is a drug of choice for newlinehyperlipidemia. Its clinical efficacy is limited due to its low aqueous solubility, incomplete absorption, short-half life, first pass metabolism, low bioavailability, and adverse effects newlineetc. newlineObjective: The objective of the present study was to improve the solubility of Lovastatin newlineand develop mucoadhesive film of solid dispersions for buccal delivery to enhance newlinebioavailability. newline |
| Pagination: | |
| URI: | http://hdl.handle.net/10603/337441 |
| Appears in Departments: | Faculty of Pharmacy |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 80_recommendation.pdf | Attached File | 14.42 MB | Adobe PDF | View/Open |
| bhuvaneshwari r.sharannavarm_2020_faculty of pharmacy.pdf | 14.42 MB | Adobe PDF | View/Open |
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