Synthesis and Characterization of Gelatin Nanohydroxyapatite Diosmin Composite Scaffold for Bone Tissue Repair in Vitroand in Vivo

Abstract

Autografts are considered to be the golden standard for tissue regeneration. Non-availability of a large volume of cells and repeated surgeries are the major drawback of autografts. Thus, quest for finding a plausible alternative with regeneration potential similar to autografts are been carried out. Bone tissue engineering (BTE) using a combination of material, cells, and growth factors/bioactive moleculesis now considered to be the promising alternative for autografts newline