Study on Phytochemistry Ethanomedicine and Pharmacological Activities of Traditionally used Selected Medicinal Plants

Abstract

Citrullus colocynthis is a species belonging to the botanical family of Cucurbitaecea; it is a newlinemedicinal plant known for their various healing properties. We investigated the effects of the newlinefixed oil extracted from the seeds in rats by monitoring blood homeostasis and body weight as newlinewell as toxicity. newlineAnimals were given daily 4% of dietary regimen of the C. colocynthis oil for 8 weeks showed newlinesignificant slowdown of the body weight evolution comparatively to the animal control group newlinereceived 4% of sunflower oil. Furthermore, colocynth oil treatment had a tendency to increase newlinesignificantly food intake feces output and lipid feces. newlineIn parallel, the serum cholesterol, triglycerides, ALP levels and the count of erythrocytes and newlinehaematocrit level decreased significantly by 15.38, 22.22,46.29, 14.97 and 14.17%, compared to newlinecontrol values, respectively; while AST level increased significantly by 21.71%. These results newlinesupport the suggestion of using C. colocynthis oil as a treatment for dyslipidemia and newlinehyperglycemia, and related abnormalities. The chronic toxicity and the mode of action of this oil newlinemust be studied. newlineDelonix regia, a well known plant with high medicinal value, reported to have a number of newlinebiological activities including antioxidant and presence of flavonoids in its chemical constituents. newlineAntioxidant property and flavonoids have been associated with wound healing actions of plants. newlineThe present study was done to investigate the wound healing properties of Delonix regia in newlineexperimental animal models. The ethanol and aqueous extracts of Delonix regia flowers were newlineprepared to study the effect on wound healing in albino rats using incision and excision wound newlinemodels.