Radiological assessment of liver damage using soft computing

Abstract

Liver is one of the largest and important organs in the human body which comprises of two granular lobes, one to the right and other to the left. It occupies a huge place on the upper right area in the abdomen. The vital role played by the liver organ includes removing waste products from human food, bile production, metabolic functions, blood purification by sensitizing digestion control and storage of vitamins and minerals. It is the essential organ for glycogen storage, hormone production, etc... Liver can be affected by various diseases and its chronic stage or liver dysfunction demands immediate medical attention. The chronic liver disease (CLD) depicts the major public health issue, noticing significant morbidity and mortality threat worldwide. CLD is estimated worldwide with a count upto 844 million people and has a mortality rate of about 2 million per year. CLD indicates the inflammatory condition of the liver which leads to cirrhosis or even partial or total liver dysfunction. The progression of this prognosis can lead to higher level of risk in developing liver failure. The most common liver diseases are fatty liver, fibrosis, cirrhosis, liver cancer, metastasis, etc Most of the hepatological issues arise gradually and can be diagnosed either by invasive or non-invasive approaches. An invasive diagnostic method is liver biopsy that is considered as the gold standard for the accurate estimation of liver diseases. Non-invasive methods such as Blood Serum Markers and Medical Imaging (Ultrasound - US, Magnetic Resonance MR and Computed Tomography - CT) for the assessment of liver diseases have emerged. newline