Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/331159
Title: | Self assembled peptide and organic framework based nano micro constructs design synthesis and potential applications |
Researcher: | Brar, Surinder Kaur |
Guide(s): | Sharma, Rohit Kumar and Nishima |
Keywords: | Amino acid Dye adsorption Peptide Peptoid Self-assembly |
University: | Panjab University |
Completed Date: | 2020 |
Abstract: | This research focused on elucidating in-depth molecular mechanisms behind high fat-low protein diet (HFLPD)-induced metabolic syndrome (MetS) and associated cognitive impairments in rat and mouse models. HFLPD and 15% oral fructose led to the development of MetShallmarks along with altered cognitive functions.Furthermore, the administration of dual PPAR-and#945;/and#947; agonists i.e., sesamol and saroglitazar, significantly upregulated peripheral and brain insulin signaling, thereby reversing the HFLPD-induced neurometabolic alterations in animal models. The findings of this work encourage consumption of a balanced diet to reduce the prevalence of metabolism-related diseases and their consequences on other organ systems. newline |
Pagination: | xxx, 317p. |
URI: | http://hdl.handle.net/10603/331159 |
Appears in Departments: | Department of Chemistry |
Files in This Item:
File | Description | Size | Format | |
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01_title.pdf | Attached File | 5.44 kB | Adobe PDF | View/Open |
02_certificate.pdf | 927.03 kB | Adobe PDF | View/Open | |
03_abstract.pdf | 176.62 kB | Adobe PDF | View/Open | |
04_acknowledgements.pdf | 287.4 kB | Adobe PDF | View/Open | |
05_contents.pdf | 191.02 kB | Adobe PDF | View/Open | |
06_list of abbreviations.pdf | 275.49 kB | Adobe PDF | View/Open | |
07_list of figures.pdf | 326.74 kB | Adobe PDF | View/Open | |
08_list of schemes.pdf | 90.39 kB | Adobe PDF | View/Open | |
09_list of tables.pdf | 17.68 kB | Adobe PDF | View/Open | |
10_chapter 1.pdf | 4.13 MB | Adobe PDF | View/Open | |
11_chapter 2.pdf | 5.25 MB | Adobe PDF | View/Open | |
12_chapter 3.pdf | 4.05 MB | Adobe PDF | View/Open | |
13_chapter 4.pdf | 8.44 MB | Adobe PDF | View/Open | |
14_chapter 5.pdf | 7.98 MB | Adobe PDF | View/Open | |
15_chapter 6.pdf | 1.23 MB | Adobe PDF | View/Open | |
16_chapter 7.pdf | 4.92 MB | Adobe PDF | View/Open | |
17_summary.pdf | 465.43 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 465.43 kB | Adobe PDF | View/Open |
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