Evaluation and characterization of herbal extract of Halodule uninervis and its diabetic activity study

Abstract

Natural products play the most significant role in the drug discovery and drug development process. The medicinal plants are best source of treatment of illness and it can be traced back by the written documents evidence of the early civilizations for long period of time in India. Marine flowering plants Seagrasses are capable of completing their life cycle when they are submerged in sea water. Ecosystem of Seagrass is one of the most widespread coastal vegetation types as compared to the ecosystems of coral and mangrove. Phytochemical study on sea grasses has clearly shown that seagrasses have pharmaceutically active secondary metabolites. Different studies on these seagrass metabolites proven that the extracted active components from seagrasses have alkaloids, glycosides, galactomannan gum, polysaccharides, peptidoglycan, hypoglycans, guanidine, steroids, carbohydrates, glycopeptides, terpenoids, amino acids and inorganic ions which directly or indirectly have a effective action aganst infection, pharmaceutically active hypolipemic agents, reduce blood pressure, and blood cholesterol levels. Phenolic compounds are effective secondary metabolites of seagresses which play a main role in various bio relevant activities in human body maintenance. The presence of phytoconstituents, such as flavonoids, phenols, and tannin, in seaweeds and seagrasses indicates a possibility that extracts may have antioxidant activity and anti diabetic activity. Marine organisms offer a wide source to discover useful therapeutics with cost effective. Thus, the study was carried out based on the minimal available data and may not be adequate enough to explain about many other pharmacological activity of the plant. Therefore, continuous pharmacological studies are compulsory to provide suggestion for a safe and effective use of this plant. Recently, numerous marine metabolites with potent pharmacological properties have been identified.