Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/326750
Title: | Total Synthesis of Biologically Active Natural Products Involving Asymmetric Induction Using Chiral Catalysis |
Researcher: | Suraksha |
Guide(s): | Pandey, Satyendra Kumar |
Keywords: | Haliclamide Petromyroxol Serinolamide A |
University: | Thapar Institute of Engineering and Technology |
Completed Date: | 2017 |
Abstract: | We have described herein enantioselective approaches for the synthesis of (+)-serinolamide A, (-)-haliclamide, (+)-petromyroxol, (+)-phomonol, (+)-epi-muricatacin and (-)-6-acetoxy-hexadecanolide employed Trost s DYKAT, MacMillan organocatalyzed aldol reaction, Sharpless AD and Jacobsen s HKR reactions as key steps.. The merits of these synthetic approaches are high enantio- and diastereoselectivity with high yielding reaction steps. All the new compounds were characterized by 1H-NMR, 13C NMR, HRMS, %ee by chiral HPLC and [and#945;]D25 for all new chiral compounds. newline |
Pagination: | 142p. |
URI: | http://hdl.handle.net/10603/326750 |
Appears in Departments: | School of Chemistry and Biochemistry |
Files in This Item:
File | Description | Size | Format | |
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01_title.pdf | Attached File | 38.26 kB | Adobe PDF | View/Open |
02_certificate.pdf | 109.59 kB | Adobe PDF | View/Open | |
03_candidates declaration.pdf | 106.16 kB | Adobe PDF | View/Open | |
04_dedication.pdf | 22.82 kB | Adobe PDF | View/Open | |
05_acknowledgements.pdf | 114.09 kB | Adobe PDF | View/Open | |
06_table of contents.pdf | 100.27 kB | Adobe PDF | View/Open | |
07_abbreviations.pdf | 165.44 kB | Adobe PDF | View/Open | |
08_general remarks.pdf | 85.71 kB | Adobe PDF | View/Open | |
09_abstract.pdf | 337.84 kB | Adobe PDF | View/Open | |
10_chapter 1.pdf | 359.75 kB | Adobe PDF | View/Open | |
11_chapter 2.pdf | 5.16 MB | Adobe PDF | View/Open | |
12_chapter 3.pdf | 1.27 MB | Adobe PDF | View/Open | |
13_chapter 4.pdf | 982.42 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 1 MB | Adobe PDF | View/Open |
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