Green Synthesis Optimization and Evaluation of Gold Nanoparticles Using Biopolymer

Abstract

Due to unique inherent catalytic characteristics of different size, shape and surface functionalized gold nanoparticles, their potential applications, are being explored in various fields such as drug delivery, biosensor and theranostics applications. However conventional process for synthesis of these metallic nanoparticles utilizes toxic reagents as reducing agents, additional capping agent for stability as well as surface functionalization for drug delivery purposes. Hence, a novel method for green synthesis of gold nanoparticles using novel gum Ghatti biotemplate as reducing, stabilizing and capping purposes, a commonly used and safe edible gum, was thoroughly explored. Although, conventionally used reducing and capping reagents of synthetic origin, are usually environmentally hazardous and toxic for living organism. But, in absence of suitable capping agent; stability, shelf life and catalytic activity of metallic nanoparticles adversely affected. However, polymeric templates which emerged as suitable choice of agent for both reducing and capping purposes; bearing additional advantages in terms of catalyst free one step green synthesis process with high degree of biosafety and efficiency. Briefly, aqueous solution of gum Ghatti prepared in different strengths were prepared and employed in the synthesis of stable gold nanoparticles via hydrothermal (conventional heating) and microwave based reduction method. Here, microwave irradiation (MI) was used which leading into characteristically enabling and extremely rapid inand#8208;core heating of dipoles and ions, in comparison to conventional thermal (conductance) process of heat transfer. Hence, during the process of nanoparticles synthesis, MI both modulates functionality behaviors as well as dynamic of reaction in favorable direction. Subsequently, MI providing a facile, favorable and alternative ix | newlineapproaches during nanoparticles synthesis nanoparticles with enhanced catalytic performances. Another aspect of current works was to understand role of process variab