Coproduction of two new peptide antibiotics and specific protease by a bacterial isolate paenibacillus alvei np75 through ribosomal and nonribosomal mediated protein synthesis machinery

Abstract

Since 1928 different types of antibiotics have been isolated and newlinepurified from the commonly available microbial sources like bacteria and newlinefungi Such popular antibiotic drugs include penicillin streptomycin newlinechloramphenicol vancomycin erythromycin polymyxin and bacitracin etc newlineSimilarly various antimicrobial antibacterial proteins and immunomodulatory newlinecompounds routinely used in chemotherapy have been isolated newlinefrom the variety of medicinal plants mammals and seaweeds Even though newlinethere are number of antibiotics being produced and marketed globally the newlinethrust for identification and screening of new antibiotics becomes extensive newlineand unquenchable newline newline