Studies on the mechanism and induction of Apoptosis by new chemical entities against Breast or Lung Cancer

Abstract

The main objective of this work is to investigate the molecular mechanism and apoptotic pathway of podophyllotoxin derivatives against human lung cancer cells A549. Further, this study was aimed newlineto investigate the molecular mechanism and apoptotic pathway of benzimidazole oxindole derivatives, benzo[b]furan derivatives and 2-aryl benzimidazole derivative against human breast cancer cells MCF-7.