Synthesis and Characterization of New Antimicrobial Conjugates and Catalytic Activity of Pb II Salts

Abstract

The work embodied in the thesis entitled Synthesis and Characterization of New Antimicrobial Conjugates and Catalytic Activity of Pb(II) Salts has been divided into six chapters. A review on recent developments of benzothiazole derivatives is described in Chapter 1. Chapter 2 deals with synthesis of new 1,2,3-triazole linked chalcone and flavone conjugates and evaluation of antimicrobial and cytotoxic activities. Design, synthesis and antibacterial evaluation of ciprofloxacin tethered bis-1,2,3-triazole conjugates is discussed in Chapter 3. A synthetic method of 5-substituted 1H-tetrazoles via Pb(II) salts catalyzed [3+2] cycloaddition of nitriles and sodium azide is described in Chapter 4. Chapter 5 describes X-ray crystallographic studies of aniline, 4-oxo-1,4-dihydroquinoline, chalcone, flavone and benzothiazole derivatives. Synthesis, characterization and DFT studies of 2-aminobenzothiazole and aniline derivatives are described in Chapter 6 newline