Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/286980
Title: | Efficacy and safety administration of lacosamide in the treatment of refractory partial epilepsy in pediatric patients |
Researcher: | Ismail Pasha |
Guide(s): | Suresh D.K. |
Keywords: | Clinical Pre Clinical and Health,Pharmacology and Toxicology,Pharmacology and Pharmacy |
University: | Jawaharlal Nehru Technological University, Hyderabad |
Completed Date: | 2015 |
Abstract: | A single centre, prospective study was performed to investigate the efficacy and safety of lacosamide as add on therapy in pediatric patients with refractory partial epilepsy.The study was done at Dr. Prabhakar Kore, tertiary care hospital over a period of 30 months duration from Nov 2011 to May 2014. Seventy-nine newlinepatients with refractory partial epilepsy (age 5 - 15 years), who had not newlineresponded to more than 2 antiepileptic medications and in whom lacosamide newlinewas used as add on drug were enrolled. Lacosamide tablets were administered newlineorally, for one week at a dose of 25 mg twice a day followed by 50 mg twice newlinedaily for the remaining period. Efficacy, safety and tolerability was assessed newlineduring titration (one month), treatment phase (three months), and subsequent newlinetwo follow up visits of one month each. Liver function tests (SGOT and SGPT) newlineand EEG were done before enrollment and at the end of treatment period. Patient s care takers or principal investigator observed for any adverse events and recorded the data in the predesigned adverse event form. newline |
Pagination: | |
URI: | http://hdl.handle.net/10603/286980 |
Appears in Departments: | Faculty of Pharmaceutical Sciences |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 170.21 kB | Adobe PDF | View/Open |
02_declaration.pdf | 279.32 kB | Adobe PDF | View/Open | |
03_certificate.pdf | 854.22 kB | Adobe PDF | View/Open | |
04_acknowledgement.pdf | 166.48 kB | Adobe PDF | View/Open | |
05_abstract.pdf | 184.63 kB | Adobe PDF | View/Open | |
06_contents.pdf | 213.07 kB | Adobe PDF | View/Open | |
07_list of tables and figures.pdf | 165.48 kB | Adobe PDF | View/Open | |
08_chapter 1.pdf | 266.19 kB | Adobe PDF | View/Open | |
09_chapter 2.pdf | 131.2 kB | Adobe PDF | View/Open | |
10-chapter 3.pdf | 742.21 kB | Adobe PDF | View/Open | |
11-chapter 4.pdf | 376.62 kB | Adobe PDF | View/Open | |
12-chapter 5.pdf | 1.53 MB | Adobe PDF | View/Open | |
13-chapter 6.pdf | 435.89 kB | Adobe PDF | View/Open | |
14-chapter 7.pdf | 192.53 kB | Adobe PDF | View/Open | |
15-chapter 8.pdf | 152.23 kB | Adobe PDF | View/Open | |
16-bibliography.pdf | 242.64 kB | Adobe PDF | View/Open |
Items in Shodhganga are licensed under Creative Commons Licence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).
Altmetric Badge: