Studies on mixed ligand complexes of Transition metals

Abstract

The field of coordination chemistry is growing exponentially in the newlinerecent years especially the complexation of transition metals with bioligands newlineTransition metals are essential for the normal functioning of living newlineOrganisms The interaction of transition metal ions with bio ligands involved newlinein many physiological processes representing an interesting topic of research newlineThe biological activities of transition metals are mainly due to the formation newlineof metal complexes with different bioligands A large number of metal newlinecomplexes are found to exhibit anti bacterial anti tumor and anti cancer newlineactivities Synthesis of new Schiff bases and their mixed ligand complexes are newlinethe aim of many recent investigations In this work mixed ligand complexes newlineusing bio ligands were synthesized characterized and their biological and newlineDNA cleavage activities were investigated The stability constants of mixed newlineligand complexes were determined using pH metric studies newline newline