Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/271168
Title: Synthesis and characterization of ZnO nanostructured materials in the presence of Inorganic and Biomolecules
Researcher: Baljinder Singh
Guide(s): Saini, G. S. S.; Gurinder Singh and Aman Kaur
Keywords: Physical Sciences,Physics,Physics Multidisciplinary
Zinc Oxide
Nanoparticles
Surfactants
Biomolecules
Cytotoxicity
University: Panjab University
Completed Date: 2018
Abstract: Nanoscale compound of zinc oxide (ZnO) was widely used after the term nanotechnology was introduced. So, here we consider the case of ZnO it is a well-studied semiconductor with potential applications in biosensing. Various properties of ZnO, such as catalytic properties, chemical stability, and surface electronic structure, depend on its polarity. Generally, the positively Zn2+- terminated (0001) and negatively O2and#8722;-terminated newline(000and#299;) polar surfaces have high surface energies. However, the polar surfaces with high surface energies will gradually diminish with crystal growth, which results from the minimization of surface energy. After preparation of surfactants (sodium dodecyl sulphate, Tween 80 and Triton X-100) coated ZnO thin films by wet chemical method, their electrical properties have been studied at different temperatures. We also report a Nobel synthesis of ZnO nanowirs by wet chemical technique of zinc acetate in xylene solvent in the presence of sodium dodecyl sulfate, which produces relatively monodisperse ZnO nanowires with uniform structure and straight morphologies. Understanding the influence of amino acids on ZnO nanoparticle behavior is thus important for predicting their biomedical fate and understanding how chemical components influence nanomaterial behavior. However, the interactions of biomolecules with the ZnO surface are complex involving the reactions of biomolecules, metal ions and water. In this work, experimental approach are performed for three different amino acids- Histidine, Arginine and Aspartic acid coated ZnO nanostructures to explain the growth mechanism of nanoparticles of different shapes. Based on the results, a plausible mechanism of formation of nanostructures has been proposed. The nanostructures with rod like morphology are found to be biocompatible with normal red blood cells and show cytotoxic effect as evaluated from hemolysis and cytotoxicity assays on breast (MCF- 7, T47D, MDA-MB-231) and prostate cancer (PC-3) cell lines. newline newline
Pagination: xvii,145p.
URI: http://hdl.handle.net/10603/271168
Appears in Departments:Department of Physics

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02_certificate.pdf630.55 kBAdobe PDFView/Open
03_acknowledgements.pdf86.06 kBAdobe PDFView/Open
04_list of publications.pdf164.37 kBAdobe PDFView/Open
05_papers presented in internationalnational conferences symposium.pdf141.87 kBAdobe PDFView/Open
06_contents.pdf101.79 kBAdobe PDFView/Open
07_list of figures.pdf169.99 kBAdobe PDFView/Open
08_list of tables.pdf151.75 kBAdobe PDFView/Open
09_list of schemes.pdf81.15 kBAdobe PDFView/Open
10_abstract.pdf161.2 kBAdobe PDFView/Open
11_chapter 1.pdf1.03 MBAdobe PDFView/Open
12_chapter 2.pdf1.44 MBAdobe PDFView/Open
13_chapter 3.pdf2.75 MBAdobe PDFView/Open
14_chapter 4.pdf2.75 MBAdobe PDFView/Open
15_chapter 5.pdf172.44 kBAdobe PDFView/Open
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