1. Shodhganga@INFLIBNET
  2. Sri Ramachandra Institute of Higher Education and Research
  3. Medical College
Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/235727
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DC FieldValueLanguage
dc.coverage.spatialReproductive medicine
dc.date.accessioned2019-03-28T04:56:13Z-
dc.date.available2019-03-28T04:56:13Z-
dc.identifier.urihttp://hdl.handle.net/10603/235727-
dc.description.abstractThe objective of the study was to assess the conservative effects of antioxidant L Ergothioneine on the post thaw chromatin integrity and functional parameters of human spermatozoa 400 normozoospermic semen samples were cryopreserved with and without supplementation of EGT Clinically relevant tests such as Semen analysis according to WHO 2010 Sperm chromatin integrity and Lipid peroxidation status assessment were performed in both fresh and frozen thawed samples It was seen that with the increase in ROS production due to cryopreservation there is a significant decrease in the post thaw sperm parameters and sperm chromatin integrity and the extent of which was reduced on addition of EGT The increasing ROS levels correlated directly with DNA damage Hence the study provides a basal proof that EGT acts against the ROS and conserves the spermatozoa functionality newline
dc.format.extent1-188
dc.languageEnglish
dc.relation
dc.rightsself
dc.titleEffect of pre freeze supplementation of novel ant oxidation L Ergothioneine on chromatin integrity and functional parameters of frozen human sperm
dc.title.alternative
dc.creator.researcherYamini Asokan
dc.subject.keywordClinical Pre Clinical and Health,Clinical Medicine,Obstetrics and Gynecology
dc.description.noteIntroduction p.1-3 Review of literature p. 4-65 Aim and Objective p. 66 Methodology p.67-75 Results p.76- 132 Discussion p.133-144 Summary p.145-146 Conclusion p. 147 Scope for future work p.148 Bibliography p.149-173
dc.contributor.guideSanjeeva Reddy. N
dc.publisher.placeChennai
dc.publisher.universitySri Ramachandra Institute of Higher Education and Research
dc.publisher.institutionMedical College
dc.date.registered01/07/2014
dc.date.completed13/03/2019
dc.date.awarded13/03/2019
dc.format.dimensions20cms
dc.format.accompanyingmaterialNone
dc.source.universityUniversity
dc.type.degreePh.D.
Appears in Departments:Medical College

Files in This Item:
File Description SizeFormat 
certificates.pdfAttached File419.81 kBAdobe PDFView/Open
chapter 10 bibliography.pdf281.85 kBAdobe PDFView/Open
chapter 11 appendices.pdf181.34 kBAdobe PDFView/Open
chapter 1 introduction.pdf105.92 kBAdobe PDFView/Open
chapter 2 review of literature.pdf1.33 MBAdobe PDFView/Open
chapter 3 aim and objective.pdf53.8 kBAdobe PDFView/Open
chapter 4 methodology.pdf204.3 kBAdobe PDFView/Open
chapter 5 results.pdf662.86 kBAdobe PDFView/Open
chapter 6 discussion.pdf204.18 kBAdobe PDFView/Open
chapter 7 summary.pdf38.45 kBAdobe PDFView/Open
chapter 8 conclusion.pdf78.83 kBAdobe PDFView/Open
chapter 9 scope of further work.pdf35.33 kBAdobe PDFView/Open
contents.pdf174.39 kBAdobe PDFView/Open
title.pdf86.48 kBAdobe PDFView/Open
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