Shodhganga : a reservoir of Indian theses @ INFLIBNET
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http://hdl.handle.net/10603/221499
| Title: | Bioequivalence and Safety Evaluation of Imatinib mesylate Tablets in Patients of Philadelphia Chromosome Positive Chronic Myeloid Leukemia |
| Researcher: | Arora, Rachna |
| Guide(s): | Monif, Tausif |
| Keywords: | Life Sciences; Bioavailability; Thyroid gland cancer; Lymphomas; Myeloid leukemia; |
| University: | Jamia Hamdard University |
| Completed Date: | 2016 |
| Abstract: | The current study was designed to characterize the pharmacokinetic profile and to assess newlinebioequivalence of the sponsor s Test formulation (Imatinib mesylate 400 mg tablets) with newlineReference Listed product (Gleevec® 400 mg tablets, Novartis Pharmaceuticals) under newlineFed conditions, in adult patients of Philadelphia chromosome positive Chronic Myeloid newlineLeukemia (Ph+ CML) stabilized on Imatinib mesylate 400 mg. In addition, study was newlineaimed to monitor safety profile of Investigational Medicinal Products (IMPs). newlineit The study has concluded that Test product Imatinib mesylate 400mg tablets newlinemanufactured for Ranbaxy Laboratories Limited, India is bioequivalent and safe, and can be used interchangeably in clinical practice. newline |
| Pagination: | |
| URI: | http://hdl.handle.net/10603/221499 |
| Appears in Departments: | Department of Pharmaceutical Chemistry |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| abbreviations.doc | Attached File | 170.04 kB | Microsoft Word | View/Open |
| certificate.doc | 120.56 kB | Microsoft Word | View/Open | |
| ch3 introduction 1-5.pdf | 144.1 kB | Adobe PDF | View/Open | |
| ch4 objective 6-7.pdf | 105.08 kB | Adobe PDF | View/Open | |
| ch5 literature review 8-62.pdf | 2.12 MB | Adobe PDF | View/Open | |
| ch6 materials and methods 63-107.pdf | 2.58 MB | Adobe PDF | View/Open | |
| ch7 results 108-176.pdf | 2.5 MB | Adobe PDF | View/Open | |
| ch8 discussion 177-188.pdf | 194.26 kB | Adobe PDF | View/Open | |
| ch9 summary and conclusion 189-191.pdf | 112.92 kB | Adobe PDF | View/Open | |
| figures.doc | 219.69 kB | Microsoft Word | View/Open | |
| tables.doc | 465.2 kB | Microsoft Word | View/Open | |
| title.doc | 1.6 MB | Microsoft Word | View/Open | |
| toc.doc | 636.34 kB | Microsoft Word | View/Open |
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