Development Characterization Processing and Testing of Quantum Dots for Imaging in Visible and Near Infrared Range

Abstract

Quantum dots are fluorescent materials. These are of very interest because of their unique and tunable optical properties. Light emitting behavior of these QDs can be tuned because of quantum confinement effect. Fluorescent behavior of QDs makes them useful in biological fields like bio imaging, cell tracking, cell targeting and FRET. This thesis includes synthesis, characterization, processing and testing of QDs for imaging in visible and NIR range. We have synthesized visible CdSe, ZnS, CdSe/ZnS and NIR CdTe QDs. After this we have processed surface of these prepared QDs by different polymeric materials and silicates. These prepared materials were tested for their toxic effects toward human kidney cell line (HEK-293). newline 1st chapter introduces about visible, NIR QDs and core shell structures and also includes steps which should be addressed before applying these QDs for bio-applications such as different methods of processing of QDs. 2nd chapter provides detailed information about synthesis methodology for QDs and their encapsulated structures and characterization. 3rd chapter includes the results obtained for CdSe stabilized by 2-Mercaptoethanol (2-M.E.) and their polymer encapsulated structures. 4th chapter involves XRD, TEM, EDX, PL and FTIR results obtained for ZnS1 and ZnS2 and CdSe/ZnS1 and CdSe/ZnS2 structures. 5th chapter contains results acquired for CdTe (NIR QDs) stabilized by 3-Mercaptopropionic acid (3-MPA) and their polymer encapsulated structures. 6th chapter involves results of toxic effect of CdSe QDs and CdTe QDs and antimicrobial behavior of CdSe and CdTe based nanostructures. 7th chapter Finally chapter 7 described the overall conclusion of thesis. newline newline