1. Shodhganga@INFLIBNET
  2. Narsee Monjee Institute of Management Studies
  3. Department of Pharmacy
Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/199013
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dc.coverage.spatial
dc.date.accessioned2018-04-05T05:47:04Z-
dc.date.available2018-04-05T05:47:04Z-
dc.identifier.urihttp://hdl.handle.net/10603/199013-
dc.description.abstractThe clinical efficacy of PLDN was limited by its poor solubility. The marketed preparations focused on extended the release of drug dosage forms with an objective to develop once a day dosing formulation. However, the poor bioavailability (28%) of the commercial dosage form (ER tablets) due to poor solubility and less intestinal absorption remains unaddressed. Therefore, the aim of this research work was to provide a suitable solubility enhancement technique(s) to resolve poor solubility problem associated with PLDN. Another objective of the current research work was to develop a novel, patient compliant and efficacious nasal drug delivery system with an intention to provide rapid onset of action and improved bioavailability newline
dc.format.extent
dc.languageEnglish
dc.relation
dc.rightsuniversity
dc.titleSolubility Enhancement and Formulation Development of Paliperidone
dc.title.alternative
dc.creator.researcherSherje Atul P.
dc.subject.keywordBrain chemistry
dc.subject.keywordIntranasal Drug Delivery Systems
dc.subject.keywordMechanism of Nasal Absorption
dc.subject.keywordPharmacological
dc.subject.keywordSchizophrenia
dc.description.note
dc.contributor.guideLondhe Vaishali
dc.publisher.placeMumbai
dc.publisher.universityNarsee Monjee Institute of Management Studies
dc.publisher.institutionDepartment of Pharmacy
dc.date.registered10/08/2011
dc.date.completed2016
dc.date.awarded
dc.format.dimensions
dc.format.accompanyingmaterialDVD
dc.source.universityUniversity
dc.type.degreePh.D.
Appears in Departments:Department of Pharmacy

Files in This Item:
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10. chapter 3- research envisaged & plan of work 8 jan.pdfAttached File211.42 kBAdobe PDFView/Open
11. chapter 4_experimental final revised.pdf755.45 kBAdobe PDFView/Open
12. chapter 5_results and discussion revised.pdf5.89 MBAdobe PDFView/Open
13. chapter 6_summary & conclusions 8 jan.pdf176.23 kBAdobe PDFView/Open
14. chapter 7_references 8 jan.pdf279.11 kBAdobe PDFView/Open
15. list of publications.pdf186.43 kBAdobe PDFView/Open
1. cover page 8 jan.pdf197.79 kBAdobe PDFView/Open
2. certificate_pages 8 jan.pdf217.87 kBAdobe PDFView/Open
5. abbreviations 8 jan.pdf189.2 kBAdobe PDFView/Open
6. list of tables final 8 jan.pdf259.29 kBAdobe PDFView/Open
7. list of figures 8 jan.pdf258.13 kBAdobe PDFView/Open
8. chapter 1_introduction_8 jan.pdf382.21 kBAdobe PDFView/Open
9. chapter 2_literature review 8 jan.pdf310.19 kBAdobe PDFView/Open
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