Adrenergic receptors and monoamines in the brain and pancreatic islets of streptozotoein diabetic rats Role in insulin secretion as a function of age

Abstract

newline The Author tries to study the changes in the content of brain rrrorroamirres in streptozotocin-induced newlinediabetes tliabetes as a lirnction of age and to find the role of adrenal hormones in diabetic state. newlineTo assess the adrenergic receptor function in the brain stem ofstreptozotocin-induced newlinediabetic rats ofdillerent ages.To study the changes in the basal levels of second messenger cAMP in the brain stenr ofstreptozotocin-induced diabetic rats as a function of age.To study the changes occurring in the content ofmorroamines and their metabolites in newlinewhole pancreas and isolated pancreatic islets of streptozotocin-diabetic rats as a function newlineofage and the effect of adrenal hormones. newlineTo study the adrenergic receptors and basal levels of cAMP in isolated pancreatic islets newlinein young and old streptozotoein-diabetic rats. newlineThe in virro study of CAMP content in pancreatic islets of young and old rats and its newlineellect on glucose induced insulin secretion. newlineThe in vitro study on the involvement of dopamine and cortico steroids in glucose newlineinduced insulin secretion in pancreatic islets as a function of age. newline