An efficient route to Acylation using TFAA- H3PO4 and its application to the synthesis of derivatives of NSAIDS

Abstract

The thesis entitled An efficient route to acylation using TFAAH3PO4 newlineand its application to the synthesis of derivatives of NSAIDs newlineis divided into five chapters. newlineCHAPTER 1 newlineA brief review of different acylating techniques with their merits newlineand de-merits newlineThis chapter deals with general survey of the literature related to newlinethe present topic which describes conventional, non-conventional and newlinegreen synthetic methods of acylation along with their merits and demerits. newlineCHAPTER 2 newlinePart A: TFAA-H3PO4 mediated synthesis of 2-acylthiophenes with newlinetheir merits and de-merits newlinePart B: TFAA-H3PO4 mediated synthesis of 2-acylfurans with their newlinemerits and de-merits newlineThis chapter is divided in to two sec