Analysis of brain ventricular shape Changes in alzheimer mr images using Reaction diffusion level set

Abstract

Alzheimers Disease AD is a fatal neurodegenerative disorder that newlinecauses cognitive impairment in people and poses challenges in performing newlineday today activities Although it is incurable the correct identification of newlineprodromal stage AD also called as Mild Cognitive Impairment MCI would newlinehelp in slow down the disease progression and develop appropriate disease newlinetherapies Presently AD is clinically diagnosed using clinical dementia rate newlineand minimental state examination. Accurate diagnosis of AD is possible only newlinethrough brain autopsy newlineInitial manifestation of AD takes place in the regions of cortex and newlinehippocampus followed by the atrophy of temporal parietal and frontal newlineneocortices Analysis of alterations in brain structures plays a important role newlinein the early diagnosis of MCI subjects newline newline