Novel drug delivery system of eugenol against inflammation and periodontal infections

Abstract

The present study aims to develop and evaluate novel drug delivery systems of eugenol against inflammation and periodontal infections. Two drug delivery systems have been investigated (i) the development of a nanoemulsion gel topical drug delivery system of eugenol for its anti-inflammatory activity and its pharmacodynamic evaluation; (ii) the formulation of a nanoparticulate drug delivery system of eugenol for periodontal disease. The researcher has concluded that whereas the performance of the developed eugenol nanoemulsion gels are found to be promising for the treatment of inflammation, the eugenol-loaded polycaprolactone nanoparticles could serve as a novel colloidal drug delivery system for the treatment of periodontal infections.