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http://hdl.handle.net/10603/10019
Title: | Synthesis of biologically important functionalized nitrogen containing heterocyclic compounds |
Researcher: | Surasani, Rajendra |
Guide(s): | Chandra Sekhar K B Kalita, Dipak |
Keywords: | biologically important compounds Nitrogen containing heterocyclic compounds |
Upload Date: | 19-Jul-2013 |
University: | Jawaharlal Nehru Technological University, Anantapuram |
Completed Date: | 20/08/2012 |
Abstract: | The thesis entitled Synthesis of biologically important functionalized nitrogen containing heterocyclic compounds is divided into ten chapters. Chapter 1 deals with general survey of literature on the importance and synthesis of the nitrogen containing heterocyclic compounds. Chapter 2 gives the objective of the work on synthesis of N-hetero cyclic compounds we planned to synthesize. The chapters 3, 4, 5, 6, 7 and 8 deals with the general survey of literature on the importance and synthesis of a particular group of nitrogen heterocyclic compounds, detailed methodology and experimental procedures followed for the synthesis of those heterocyclic compounds. In chapter 9 and 10 gives the details of the thesis summary and conclusion. Chapter 1: Introduction to N-Heterocycles This chapter describes an overview of available literature on the biological activity. Chapter 2: Aim and Objective This chapter describes an overview of the work on evaluation of N-heterocyclic compounds we chose for the synthesis and importance of green chemistry. Chapter 3: One-pot synthesis of polyhydroquinolines In this chapter we have discussed on the pharmacological importance of polyhydroquinolines and also reviewed on previous synthetic methods. An efficient and straight forward general method has been developed for the synthesis of polyhydroquinolines by simply combining aldehyde, alkyl acetoacetate, and#945;-keto compounds including 5,5-dimethyl-1,3-cyclohexanedione or 1,3-cyclohexanedione and ammonium acetate in the presence of a catalytic amount of Iron(III) fluoride in ethanol at 75-80 °C. The process presented here is operationally simple, environmentally benign and has excellent yields with short reaction times. Furthermore, the catalyst can be recovered conveniently and reused efficiently for multiple runs. Scheme 1. Reagents and conditions: (a) FeF3, Ethanol, 75-80 °C Chapter 4: Synthesis of N-Substituted Pyrroles. |
Pagination: | 397p. |
URI: | http://hdl.handle.net/10603/10019 |
Appears in Departments: | Department of Chemistry |
Files in This Item:
File | Description | Size | Format | |
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03_abstract.pdf | Attached File | 210.09 kB | Adobe PDF | View/Open |
apendix.pdf | 521.34 kB | Adobe PDF | View/Open | |
02_certificate & declaration.pdf | 257.4 kB | Adobe PDF | View/Open | |
06_chapter -1.pdf | 568.82 kB | Adobe PDF | View/Open | |
07_chapter- 2.pdf | 561.59 kB | Adobe PDF | View/Open | |
08_chapter-3.pdf | 1.37 MB | Adobe PDF | View/Open | |
09_chapter-4.pdf | 1.22 MB | Adobe PDF | View/Open | |
10_chapter -5.pdf | 1.25 MB | Adobe PDF | View/Open | |
12_chapter -7.pdf | 1.97 MB | Adobe PDF | View/Open | |
13_chapter-8.pdf | 1.3 MB | Adobe PDF | View/Open | |
11_chaptr-6.pdf | 1.64 MB | Adobe PDF | View/Open | |
14_conclusion.pdf | 420.56 kB | Adobe PDF | View/Open | |
05_contents.pdf | 213.2 kB | Adobe PDF | View/Open | |
04_list of figures & tables.pdf | 349.87 kB | Adobe PDF | View/Open | |
15_references.pdf | 297.67 kB | Adobe PDF | View/Open | |
01_title.pdf | 17.41 kB | Adobe PDF | View/Open |
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