Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/10019
Title: Synthesis of biologically important functionalized nitrogen containing heterocyclic compounds
Researcher: Surasani, Rajendra
Guide(s): Chandra Sekhar K B
Kalita, Dipak
Keywords: biologically important compounds
Nitrogen containing heterocyclic compounds
Upload Date: 19-Jul-2013
University: Jawaharlal Nehru Technological University, Anantapuram
Completed Date: 20/08/2012
Abstract: The thesis entitled Synthesis of biologically important functionalized nitrogen containing heterocyclic compounds is divided into ten chapters. Chapter 1 deals with general survey of literature on the importance and synthesis of the nitrogen containing heterocyclic compounds. Chapter 2 gives the objective of the work on synthesis of N-hetero cyclic compounds we planned to synthesize. The chapters 3, 4, 5, 6, 7 and 8 deals with the general survey of literature on the importance and synthesis of a particular group of nitrogen heterocyclic compounds, detailed methodology and experimental procedures followed for the synthesis of those heterocyclic compounds. In chapter 9 and 10 gives the details of the thesis summary and conclusion. Chapter 1: Introduction to N-Heterocycles This chapter describes an overview of available literature on the biological activity. Chapter 2: Aim and Objective This chapter describes an overview of the work on evaluation of N-heterocyclic compounds we chose for the synthesis and importance of green chemistry. Chapter 3: One-pot synthesis of polyhydroquinolines In this chapter we have discussed on the pharmacological importance of polyhydroquinolines and also reviewed on previous synthetic methods. An efficient and straight forward general method has been developed for the synthesis of polyhydroquinolines by simply combining aldehyde, alkyl acetoacetate, and#945;-keto compounds including 5,5-dimethyl-1,3-cyclohexanedione or 1,3-cyclohexanedione and ammonium acetate in the presence of a catalytic amount of Iron(III) fluoride in ethanol at 75-80 °C. The process presented here is operationally simple, environmentally benign and has excellent yields with short reaction times. Furthermore, the catalyst can be recovered conveniently and reused efficiently for multiple runs. Scheme 1. Reagents and conditions: (a) FeF3, Ethanol, 75-80 °C Chapter 4: Synthesis of N-Substituted Pyrroles.
Pagination: 397p.
URI: http://hdl.handle.net/10603/10019
Appears in Departments:Department of Chemistry

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03_abstract.pdfAttached File210.09 kBAdobe PDFView/Open
apendix.pdf521.34 kBAdobe PDFView/Open
02_certificate & declaration.pdf257.4 kBAdobe PDFView/Open
06_chapter -1.pdf568.82 kBAdobe PDFView/Open
07_chapter- 2.pdf561.59 kBAdobe PDFView/Open
08_chapter-3.pdf1.37 MBAdobe PDFView/Open
09_chapter-4.pdf1.22 MBAdobe PDFView/Open
10_chapter -5.pdf1.25 MBAdobe PDFView/Open
12_chapter -7.pdf1.97 MBAdobe PDFView/Open
13_chapter-8.pdf1.3 MBAdobe PDFView/Open
11_chaptr-6.pdf1.64 MBAdobe PDFView/Open
14_conclusion.pdf420.56 kBAdobe PDFView/Open
05_contents.pdf213.2 kBAdobe PDFView/Open
04_list of figures & tables.pdf349.87 kBAdobe PDFView/Open
15_references.pdf297.67 kBAdobe PDFView/Open
01_title.pdf17.41 kBAdobe PDFView/Open
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