Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/37532
Title: Physicochemical Study of Antioxidant Surfactant Interaction: utilization in clotrimazole topical formulation
Researcher: Bhardwaj, Varun
Guide(s): Sharma, Poonam
Keywords: Antioxidants
Clotrimazole
Formulation
Micellization
Physicochemical Interaction
Surfactants
Upload Date: 18-Mar-2015
University: Jaypee University of Information Technology, Solan
Completed Date: 23/12/2014
Abstract: Micellar systems hold excellent drug delivery applications due to their capability to solubilize a large number of hydrophobic and hydrophilic molecules In this present work, the mixed micelle formation between three surfactants SDS, CTAB and Triton X 100 and two synthetic lipophilic antioxidants BHA and BHT have been studied in different alcohols and hydroalcoholic mediums ie 100percent 70 percent and 30 percent of MeOH, EtOH and 1 PrOH Early micellization was found with critical micelle concentration CMC shifting towards lower concentration In this context, conductance study, CMC, standard thermodynamic parameters of micellization namely , and have been evaluated at different temperatures Molar volume and compressibility measurements have also been carried out to evaluate the apparent molar volume and#61542;v and apparent molar adiabatic compression and#61542;k of BHA BHT surfactant complex and discussed in terms of the solute solute and solute solvent interactions newline
Pagination: 
URI: http://hdl.handle.net/10603/37532
Appears in Departments:Department of Pharmacy

Files in This Item:
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01_title.pdfAttached File80.02 kBAdobe PDFView/Open
04_acknowledgement.pdf357.55 kBAdobe PDFView/Open
05_list of figures & tables.pdf992.96 kBAdobe PDFView/Open
06_contents.pdf216.68 kBAdobe PDFView/Open
07_chapter 1.pdf4.16 MBAdobe PDFView/Open
08_chapter 2.pdf3.22 MBAdobe PDFView/Open
09_chapter 3.pdf3.13 MBAdobe PDFView/Open
10_chapter 4.pdf8.74 MBAdobe PDFView/Open
11_chapter 5.pdf4.09 MBAdobe PDFView/Open
12_chapter 6.pdf404.48 kBAdobe PDFView/Open
13_publications.pdf367.74 kBAdobe PDFView/Open
14_appendices.pdf4.77 MBAdobe PDFView/Open
2_certificate.pdf141.51 kBAdobe PDFView/Open
3_declaration.pdf84.95 kBAdobe PDFView/Open


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