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Title: Studies on antioxidant activities of some lichen metabolites developed in vitro
Researcher: Verma, Neeraj
Guide(s): Behera, B C
Keywords: Liver diseases, Lichens
Upload Date: 2-Sep-2011
University: University of Pune
Completed Date: April, 2009
Abstract: The oxidative metabolism of all the living organisms plants, microorganisms and humans continuously produces oxygen centered free radicals and other reactive oxygen species (ROS) in vivo, causing cell death and tissue damage which ultimately leads to many health problems like carcinogenesis, coronary heart disease, ageing, atherosclerosis, stroke, diabetes, cancer and neurodegenerative diseases such as Alzheimer’s and Parkinsonism. Every living organism has a defense system of endogenous antioxidants to combat the reactive species. These are the substances which terminate direct ROS attacks and radical-mediated oxidative reactions, and appear to be of primary importance in the prevention of diseases. But due to limited amount of endogenous antioxidants or excess production of reactive species, exogenous antioxidants are required. Minimizing the oxidative damage may well be one of the most important approaches for primary prevention of these age-associated diseases and health problems. Most of the commercially available antioxidants are synthetic ones and reported for their toxicity and carcinogenicity. So products from natural origin are came in to the light and are now considered as an alternative to the arsenal of synthetic antioxidants for the treatment of severe chronic diseases. Lichens are the symbiotic organisms composed of a fungal partner (mycobiont) in association with one or more photosynthetic partner (photobiont). They are supposed to be the most unexploited organisms on our planet. The adaptability of these organisms to extreme environmental conditions, particularly to temperature-induced ones, is of much interest for the new and effective therapeutic compounds.
Pagination: 105p.
Appears in Departments:Department of Biotechnology

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01_title.pdfAttached File115.71 kBAdobe PDFView/Open
02_list of contents.pdf119.78 kBAdobe PDFView/Open
03_acknowledgemetns.pdf120.71 kBAdobe PDFView/Open
04_declaration.pdf115.92 kBAdobe PDFView/Open
05_certificate.pdf115.97 kBAdobe PDFView/Open
06_list of tables.pdf120.17 kBAdobe PDFView/Open
07_list of figures.pdf121.12 kBAdobe PDFView/Open
08_abstract.pdf73.51 kBAdobe PDFView/Open
09_introduction.pdf150.4 kBAdobe PDFView/Open
10_chapter 1.pdf131.32 kBAdobe PDFView/Open
11_chapter 2.pdf339.72 kBAdobe PDFView/Open
12_chapter 3.pdf263.71 kBAdobe PDFView/Open
13_chapter 4.pdf792.91 kBAdobe PDFView/Open
14_chapter 5.pdf124.83 kBAdobe PDFView/Open
15_chapter 6.pdf111.67 kBAdobe PDFView/Open
16_list of publications.pdf83.85 kBAdobe PDFView/Open
17_references.pdf115.12 kBAdobe PDFView/Open
18_tables.pdf523.92 kBAdobe PDFView/Open

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