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Title: Spectroscopic and structural investigations on microwave synthesized nanostructured hydroxyapatite bioceramic materials
Researcher: Mishra, Vijay Kumar
Guide(s): Rai, S.B.
Keywords: Nanostructured Hydroxyapatite Bioceramic Materials --Spectroscopic Study
University: Banaras Hindu University
Completed Date: 2015
Abstract: Bone may be simply described as a biocomposite of organic and mineral phase components. In most bones, the weight proportions of major components are; 60-70% of mineral substances, 20- 30% of collagen and other organic components and remaining water. The organic phase of bone mostly consists of collagen and minor amounts of some important non-collageneous proteins. Bone mineral is a version of hydroxyapatite (HAp), essentially a carbonate substituted apatite. Inorganic part of bones, almost in all mammalian is HAp: Ca5(PO4)3OH or Ca10 (PO4)6(OH)2. Almost, 3-8% of the phosphate groups of HAp are replaced by carbonate. It referred as carbonated HAp (CHAp). Other trace constituents viz. magnesium, strontium, sodium, chloride and fluoride are also present. Bone also contains two types of cells; bone-forming cells (osteoblasts) and bone-resorbing cells (osteoclasts) with various osteoinductive growth factors and molecules. The HAp has attracted attention of materials scientists from past several decades, due to its crystallographic and chemical similarity with various calcified tissues of vertebrates. HAp and CHAp have been developed synthetically via various methods. HAp shows marvelous biocompatibility with hard tissues like bone and teeth as well as with soft tissues like skin and muscles without any cytoxic effect. HAp is chemically stable for long periods of time in vivo.
Appears in Departments:Department of Physics

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