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Title: Development of New and Efficient Synthetic Methods for Ploglitazone, Ranolazine, Clopidogrel, Zafirlucast and Tadalafil
Researcher: Rao, Lokeswara M
Guide(s): Rakeshwar
Mukkanti, K
Keywords: Ploglitazone
Upload Date: 16-Jun-2014
University: Jawaharlal Nehru Technological University, Hyderabad
Completed Date: 2013
Abstract: Design and development of new, efficient and commercially viable synthetic methods for the preparation of active pharmaceutical newlineingredients is an integral part of the process chemistry in the pharmaceutical industry. Therefore, in order to develop a commercial route as early as possible in the lifecycle of a compound a meticulous newlinescientific approach is required. Given the current socioeconomic and environmental concerns, commercial synthetic approaches to the active pharmaceutical ingredients (APIs) need to be safer, greener, simple, cost newlineeffective and less energy intensive. From a process development standpoint even small modification to the existing synthetic methods makes huge difference in commercial scale and these modifications directly reflect on cost of the end product. An in-depth optimization can offer huge profit in the manufacturing of drug substance. newline
Pagination: 210 p.
Appears in Departments:Department of Chemistry

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01_title.pdfAttached File99.07 kBAdobe PDFView/Open
02_dedication.pdf139.02 kBAdobe PDFView/Open
03_declaration.pdf83.27 kBAdobe PDFView/Open
04_certificate.pdf88.33 kBAdobe PDFView/Open
05_acknowledgement.pdf83.87 kBAdobe PDFView/Open
06_abstract.pdf171.01 kBAdobe PDFView/Open
07_contents.pdf102.47 kBAdobe PDFView/Open
08_abbreviations & remarks.pdf110.43 kBAdobe PDFView/Open
09_chapter 1.pdf874.7 kBAdobe PDFView/Open
10_chapter 2.pdf625.5 kBAdobe PDFView/Open
11_chapter 3.pdf1.52 MBAdobe PDFView/Open
12_chapter 4.pdf305.9 kBAdobe PDFView/Open
13_chapter 5.pdf300.17 kBAdobe PDFView/Open

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