Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/18837
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dc.coverage.spatialChemistryen_US
dc.date.accessioned2014-05-30T11:11:38Z-
dc.date.available2014-05-30T11:11:38Z-
dc.date.issued2014-05-30-
dc.identifier.urihttp://hdl.handle.net/10603/18837-
dc.description.abstractChapter-1 is about general introduction of impurities and method development. newlineChapter-2 describes about an unknown impurity formed in 50°C stability samples at 3 months in Lamivudine, Zidovudine and Nevirapine tablets for oral suspension which was detected by the new HPLC method. This degradation product was isolated by using newlinepreparative chromatography. The chemical structure of the degradant was elucidated by MS, 1H-NMR, 13C-NMR, DEPT and IR. The data newlineindicated that the structure as 1-[5-Hydroxymethyl-4-(5-methyl-2,3- dihydro-[1,2,3]triazole-1yl)-tetrahydro-furan-2-yl]-5-methyl-1Hpyrimidine- 2,4-(1H,3H)-dione. The mechanism of formation of this newlineimpurity is described in detailen_US
dc.format.extent141 p.en_US
dc.languageEnglishen_US
dc.relation-en_US
dc.rightsuniversityen_US
dc.titleMethod Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugsen_US
dc.title.alternative-en_US
dc.creator.researcherAparna, Ponnalaen_US
dc.subject.keywordCardiovascularen_US
dc.subject.keywordDosageen_US
dc.subject.keywordDrugsen_US
dc.subject.keywordImpuritiesen_US
dc.subject.keywordMulticomponenten_US
dc.description.noteNoneen_US
dc.contributor.guideThomas, K Men_US
dc.contributor.guideMukkanti, K-
dc.publisher.placeKukatpallyen_US
dc.publisher.universityJawaharlal Nehru Technological University, Hyderabaden_US
dc.publisher.institutionFaculty of Chemistryen_US
dc.date.registeredn.den_US
dc.date.completed2013en_US
dc.date.awardedn.den_US
dc.format.dimensions-en_US
dc.format.accompanyingmaterialNoneen_US
dc.type.degreePh.D.en_US
dc.source.inflibnetINFLIBNETen_US
Appears in Departments:Department of Chemistry

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01_title.pdfAttached File6.7 kBAdobe PDFView/Open
02_abstract.pdf77.67 kBAdobe PDFView/Open
03_chapter 1.pdf597.34 kBAdobe PDFView/Open
04_chapter 2.pdf517.18 kBAdobe PDFView/Open
05_chapter 3.pdf273.11 kBAdobe PDFView/Open
06_chapter 4.pdf301.54 kBAdobe PDFView/Open
07_chapter 5.pdf271.43 kBAdobe PDFView/Open
08_chapter 6.pdf347.24 kBAdobe PDFView/Open


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