Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/117987
Title: EFFECT OF DIVERSE BEHAVIORAL STATE ON MARKERS OF OXIDATIVE STRESS AND DIFFERENT BIOCHEMICAL PARAMETERS IN ANIMAL MODEL
Researcher: Mr. Deepak Suresh Mohale
Guide(s): Dr. A.V. Chandewar
Keywords: stress markers ,biochemical parameters ,anxiety and depression
University: Prist University
Completed Date: 28/06/2014
Abstract: ABSTRACT newline newline newline newlineStudy was undertaken to investigate the effect of anxiety and depression on various oxidative stress markers and biochemical parameters in rats. Rats were subjected for newline21 days, 49 days and 84 days of social isolation; the rats displayed an increase in anxiety on elevated plus maze and open field test and depression on forced swim test and tail suspension test relative to control. Various markers of oxidative stress like lipid peroxidation (LPO), reduced glutathione (GSH), Supers oxide dismutase (SOD), catalase (CAT) and biochemical parameters like SGOT, SGPT, urea, creatinine, blood lipid profile and blood sugar were determined. There was significant increase in the level of LPO and decrease in the levels of GSH, SOD and CAT after short term and long term isolation in plasma. Similarly there was significant increase in the level of LPO and decrease in the levels of GSH, SOD and CAT after long term isolation in Brain, Liver and kidney tissue. Biochemical parameters were significantly altered after long term isolation. Results indicate that increase in oxidative stress in anxiety and depression which may leads to alteration of biochemical parameters. newline newline
Pagination: A4
URI: http://hdl.handle.net/10603/117987
Appears in Departments:Department of Pharmacy

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abbreviationssymbol.pdfAttached File79.3 kBAdobe PDFView/Open
acknowlegdements.pdf86.32 kBAdobe PDFView/Open
certificates.pdf109.56 kBAdobe PDFView/Open
chapter 10.pdf52.72 kBAdobe PDFView/Open
chapter 1.pdf512.22 kBAdobe PDFView/Open
chapter 2.pdf210.81 kBAdobe PDFView/Open
chapter 3.pdf73.04 kBAdobe PDFView/Open
chapter 4.pdf75.54 kBAdobe PDFView/Open
chapter 5.pdf87.79 kBAdobe PDFView/Open
chapter 6.pdf332.8 kBAdobe PDFView/Open
chapter 7.pdf1.1 MBAdobe PDFView/Open
chapter 8.pdf109.31 kBAdobe PDFView/Open
chapter 9.pdf82.05 kBAdobe PDFView/Open
contents.pdf62.32 kBAdobe PDFView/Open
list of tables figures.pdf83.97 kBAdobe PDFView/Open
preface.pdf60.96 kBAdobe PDFView/Open
references.pdf296.76 kBAdobe PDFView/Open
title.pdf82.39 kBAdobe PDFView/Open


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