Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/68045
Title: Chemical transformations of abundant natural products
Researcher: Chowdhury, Pritish Koomar
Guide(s): Sharma, R P
Keywords: Abundant
Biological
Chemical
Chemistry
Cynaropicrin
Methylene
Orizabin
Tagitinin
University: Gauhati University
Completed Date: 31/12/1981
Abstract: Tagitinin-E has been synthesized from tagitinin-C(3), thus leading to a revised structure for tagitinin-E(7). Ciliarin (19a) and orizabin (21a) have been synthesized from tagitinin-C(3) which delineates the question about the absolute stereochemistry of the ester side chain at C-8. Since calaxin (18 ) and zexbrevin (17 ) have been correlated with orizabin and ciliarin, it has been suggested that the stereochemistry of ester side chain in these compounds should also be revised. Besides these, some correlation attempts have been described which though not leading to the desired goal gave compounds which appeared to be chemically interesting. The third part of the thesis describes the experiments aimed at synthesizing vernolepin (39) from cynaropicrin(40) and tagitinin-C(3). The behaviour of the epoxides with different Lewis acids and mineral acids have been studied which while not leading to the desired rearrangement paves a way for further designing of the experiments to synthesize vernolepin (39).
Pagination: 
URI: http://hdl.handle.net/10603/68045
Appears in Departments:Department of Chemistry

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05_acknowledgement.pdf25.35 kBAdobe PDFView/Open
06_abstract.pdf22.98 kBAdobe PDFView/Open
07_abbreviations used.pdf11.77 kBAdobe PDFView/Open
08_chapter 1.pdf880.73 kBAdobe PDFView/Open
09_chapter 2.pdf1.04 MBAdobe PDFView/Open
10_chapter 3.pdf1.13 MBAdobe PDFView/Open
11_references.pdf66.5 kBAdobe PDFView/Open


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