Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/66973
Title: Chemical investigation of meyna laxiflora robyns syn vangueria spinosa hook
Researcher: Gogoi, Jyotirekha
Guide(s): Sarma, Pabitra Kumar
Keywords: Anthraquinone
Isolation
Laxiflora
Meyna
Oleanolic
Saponins
Spinosa
Vangueria
University: Gauhati University
Completed Date: 31/12/1995
Abstract: This study presents an account of the investigation on chemical composition on Meyna laxiflora Robyns. syn. Vangueria spinosa Hook. (Family : Rubiaceae). M. laxiflora is a wild medicinal plant of Assam. The seeds of the plant were reported to be a female antifertility agent. Decotion of the leaves was used against diphtharia. The saponaceous nature of the leaves prompted people of certain parts of Assam to use it as antidandruff shampoo. The stem was recommended with other drugs in case of snake-bite and scorpio-sting. In spite of these reports on various medicinal uses, this plant species has been left almost chemically univestigated so far. Preliminary tests on the parts of the plant showed the presence of triterpenoid saponins. So, an illustrative and analytical review on triterpenoid saponins has been made. Triterpenoid saponins comprise a biologically significant class of compounds which possess a number of medicinal properties. In the review, detection, various methods of isolation of triterpenoid saponins from different plants species, structure elucidation and biological significances have been included. A comprehensive list of plants and animal sources of triterpenoid saponins reported so far and a list of triterpenoid genins, whose structures were fully elucidated have been prepared. In the experimental part, nine triterpenoid saponins have been isolated from the seeds and leaves. One anthraquinone has been isolated from the leaves. The structures of these isolated compounds have been elucidated on the basis of chemical and spectral analysis. They were named arbitrarily as ML-1, ML-2, ML-3, ML-4, ML-5, ML-6, ML-7, ML-8, ML-9 and ML-10. ML-8 was given to the anthraquinone. From the seeds, seven triterpenoid saponins, viz., ML-1 to ML-7 were isolated. The first six, ML-1 to ML-6 were found to be new and ML-7 was found to be reported earlier from Xeromphis spinosa. From the leaves, five triterpenoid saponins have been isolated. Out of these five, three are - ML-3, ML-4 and ML-7 as found in seeds. Other two
Pagination: 
URI: http://hdl.handle.net/10603/66973
Appears in Departments:Department of Chemistry

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01_title page.pdfAttached File19.16 kBAdobe PDFView/Open
02_certificate.pdf25.81 kBAdobe PDFView/Open
03_acknowledgement.pdf31.74 kBAdobe PDFView/Open
04_content.pdf17.05 kBAdobe PDFView/Open
05_abbreviations.pdf13.92 kBAdobe PDFView/Open
06_list of tables.pdf16.17 kBAdobe PDFView/Open
07_abstract.pdf67.19 kBAdobe PDFView/Open
08_chapter 1.pdf438.72 kBAdobe PDFView/Open
09_chapter 2.pdf1.79 MBAdobe PDFView/Open
10_chapter 3.pdf1.6 MBAdobe PDFView/Open


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