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Title: Evaluation of the potential of embryonic stem cells esc and their derivatives as a model for drug screening and toxicity
Researcher: Pal, Rajarshi
Guide(s): Bhonde, Ramesh R
Keywords: Embryonic Stem Cells
Embryoid Bodies
Hepatocyte Differentiation
Drug Screening
Upload Date: 26-Oct-2012
University: Manipal University
Completed Date: 05/12/11
Abstract: The present thesis focuses on the evaluation of human embryonic stem cells (hESC) as a model to understand the propensity of independently derived cell lines towards specific germ layers if any. Obtaining a purer population of desired cell type in large numbers based on this inherent potential of hESC was the next aim. Finally, this study explores the feasibility of these hESC and their derivatives in determination of toxic effects of known drugs and drug solvents so as to make available a humanized cell-based platform for drug screening and toxicity testing.
Pagination: --
Appears in Departments:Manipal Institute of Regenerative Medicine

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01_title.pdfAttached File89.89 kBAdobe PDFView/Open
02_certificate.pdf137.54 kBAdobe PDFView/Open
03_abstract.pdf80.44 kBAdobe PDFView/Open
04_declaration.pdf170.79 kBAdobe PDFView/Open
05_acknowledgement.pdf88.51 kBAdobe PDFView/Open
06_contents.pdf161.76 kBAdobe PDFView/Open
07-list of tables.pdf4.5 kBAdobe PDFView/Open
08_list of figures.pdf9.83 kBAdobe PDFView/Open
09_abbreviations.pdf150.53 kBAdobe PDFView/Open
10_objectives.pdf80.72 kBAdobe PDFView/Open
11_chapter 1.pdf365.44 kBAdobe PDFView/Open
12_chapter 2.pdf322.62 kBAdobe PDFView/Open
13_chapter 3.pdf1.09 MBAdobe PDFView/Open
14_chapter 4.pdf1 MBAdobe PDFView/Open
15_chapter 5.pdf721.01 kBAdobe PDFView/Open
16_chapter 6.pdf1.2 MBAdobe PDFView/Open
17_conclusion.pdf80.48 kBAdobe PDFView/Open
18_summary.pdf173.67 kBAdobe PDFView/Open
19_bibliography.pdf370.95 kBAdobe PDFView/Open

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